CJC-1295 without DAC is a synthetic 30-amino acid peptide analogue studied for its interactions with GHRH receptor pathways in experimental models. Also referred to as Modified GRF(1-29), the compound incorporates amino acid substitutions that confer enhanced protease resistance relative to native GHRH(1-29) while retaining GHRH receptor binding affinity. Unlike the DAC-modified variant, CJC-1295 without DAC lacks the albumin-binding moiety, producing a shorter stability window in experimental systems that is studied for its utility in research protocols modelling pulsatile growth hormone secretagogue signalling. Research applications include GHRH receptor pathway studies, pulsatile growth hormone signalling research, and comparative DAC versus non-DAC peptide pharmacology.








