MOTS-C 10mg

MOTS-C (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a 16-amino-acid peptide encoded within the mitochondrial genome’s 12S rRNA region and is classified as a mitochondria-derived peptide (MDP). Experimental investigations have examined its role in mitochondrial-to-nuclear signaling pathways, intracellular regulatory networks, and adaptive signaling mechanisms associated with mitochondrial communication systems. Research has also explored interactions with AMP-activated protein kinase (AMPK), FOXO-associated signaling pathways, transcriptional regulatory processes, and downstream signal transduction networks. Research applications include mitochondrial signaling pathway investigation, AMPK pathway characterization, FOXO signaling studies, mitochondrial communication research, and mechanistic evaluation of mitochondria-derived peptide biology.