Telmisartan, 2400mg (40mg/capsule)

Telmisartan is a biphenyl-tetrazole small molecule and selective antagonist of the angiotensin II type 1 receptor (AT1R). In addition to its well-characterized AT1R antagonism, telmisartan exhibits partial agonist activity at peroxisome proliferator-activated receptor gamma (PPARγ), distinguishing it from many other compounds within the angiotensin receptor blocker (ARB) class. This dual pharmacological profile enables investigation of both G protein-coupled receptor (GPCR) signaling and nuclear receptor-mediated transcriptional regulation within a single molecular framework.

Experimental studies have examined telmisartan’s interactions with AT1R-associated signaling pathways, PPARγ-dependent transcriptional mechanisms, receptor-ligand binding dynamics, and downstream regulatory networks. Research applications include AT1R pharmacology, angiotensin receptor signaling studies, PPARγ partial agonism research, receptor cross-talk investigation, structure-activity relationship analysis, and mechanistic evaluation of coordinated GPCR and nuclear receptor signaling systems. Supplied in capsule form.