5-Amino-1MQ (50mg/capsule), 60 Capsules

5-Amino-1MQ (5-Amino-1-methylquinolinium iodide) is a selective small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme involved in nicotinamide methylation and cellular methyl-donor utilization pathways. By inhibiting NNMT activity, 5-Amino-1MQ modulates enzymatic processes associated with nicotinamide metabolism, methylation network regulation, and intracellular cofactor-associated signaling systems. Experimental investigations have examined the relationship between NNMT inhibition and regulatory pathways involving nicotinamide turnover, methylation dynamics, transcriptional control mechanisms, and downstream signal transduction processes.

Its well-characterized pharmacological profile has established 5-Amino-1MQ as a valuable research tool for studying NNMT enzyme biology, enzyme-inhibitor interactions, methylation pathway regulation, nicotinamide-associated metabolic networks, and structure-activity relationships involving NNMT-targeting compounds. Research applications include NNMT pharmacology, methyltransferase signaling studies, enzymatic regulation investigations, and mechanistic evaluation of nicotinamide methylation pathways.