Nebivolol 300 mg (5 mg / 60 capsules)

Nebivolol is a third-generation β-adrenoceptor blocker with high β1-selectivity and a unique secondary mechanism: activation of endothelial nitric oxide synthase (eNOS) via GRK/β-arrestin biased agonism, producing vasodilation absent from earlier-generation β-blockers. Research applications include β1-AR pharmacology, biased agonism at β-adrenoceptors, eNOS activation pathway investigation, and NO-mediated vascular biology research.