Tamoxifen (20mg/capsule), 60 Capsules

Tamoxifen is a triphenylethylene-class selective estrogen receptor modulator (SERM) that exhibits ligand-dependent interactions with estrogen receptors ERα and ERβ. Experimental investigations have demonstrated that tamoxifen induces distinct receptor conformations that influence co-regulator recruitment, resulting in differential transcriptional activity across estrogen receptor signaling systems. Its well-characterized pharmacology has made it a benchmark compound for studies of estrogen receptor modulation, ligand-receptor interactions, receptor conformational dynamics, nuclear receptor signaling, and transcriptional regulation. Tamoxifen is also widely utilized in inducible CreERT2 systems, where ligand-dependent activation of modified estrogen receptor domains enables controlled recombination in genetic research models. Research applications include ERα/ERβ pharmacology, SERM mechanism investigation, co-regulator recruitment studies, inducible recombination systems, and comparative analyses of selective estrogen receptor modulators.